P Clara Jeyaseeli


The red blood cells penetrating through the veins of the human body transport the
oxygen which forms the basis for survival and if a human meets an accident or
suffers from illness, then blood transfusion comes for the rescue. The researchers
are still working towards the production of blood substitutes or artificial blood from
1600s onwards. A scientometric study on this type of research may influence the
researchers to know about the growth of this research, the prolific researchers
involved in this field, the scattering of knowledge in various sources, the language in
which the research output is delivered, the collaborative contribution from different
countries of this world which may enhance further research progress.
scientometric study uses PubMed Online database and downloaded all citations
where the period of study is not limited. The maximum growth occurs in the year
2011 with 2122 publications which is close to 3% almost. This study from 1896 to
2014 proves that the literature grows exponentially and the yearly growth is about
10.9%. The research was almost doubled from 1952 onwards with the advent of
Perfluorochemicals (PFC) in 1966. The most prolific first authors are Chang TM
from Brazil who pioneered this research followed by Boldt J from Germany and
Walter H from Germany in third rank. The researchers are interested in collaborative
research, but the solo research 13.133% is also appreciable. The degree of
collaboration is 0.868. The value of group co-efficient (g p ) is as high as 0.87, co-
authors is 0.52 in articles published by more than three authors, 0.17 for three author
publications and maximum of 0.18 in two-author publications. This scientometric
study confirms that the artificial blood research is still in the growing stage.

Keywords: Artificial blood, Blood substitutes, Scientometrics, PubMed

Full Text:



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Mahapatra, Gayatri. Bibliometric studies: in the internet era. New Delhi: India Publishing House, 2009, 61.

Narayan, Pushpa. IIT-Madras ready for mass production of artificial blood. The Times of India, 2013. [accessed 08 October 2013].

Notman, Nina. Blood substitutes - Artificial blood. Chemistry World, 40-44, 2010. [accessed 14 November 2013].

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